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Add Zurampic and do more to lower your uric acid level

ZURAMPIC is an FDA-approved pill that treats high uric acid in people with gout who are already taking allopurinol or Uloric. If your uric acid level is still too high and you continue to experience symptoms, talk to your doctor about adding ZURAMPIC to do more to lower your acid level.

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Taking ZURAMPIC

Here are some important things to know about how to take ZURAMPIC:

  • Take ZURAMPIC exactly as prescribed by your doctor
  • Take one ZURAMPIC pill each morning at the same time as your allopurinol or Uloric. Remember, you need to take both so they can work together to lower high uric acid. Taking ZURAMPIC alone could increase your risk for kidney problems. Do not take more than one ZURAMPIC pill per day
  • Take ZURAMPIC with food and water. Drink 2 liters of fluid (about 68 ounces) throughout the day while taking ZURAMPIC

While on ZURAMPIC

Gout flares may happen after starting uric acid lowering therapy, including ZURAMPIC, because of a change in your uric acid level. Your doctor may give you other medicines to help prevent flares.

Do not stop taking ZURAMPIC even if you have a flare.

If you miss a dose of ZURAMPIC in the morning, do not take it later in the day. Wait to take your next dose of ZURAMPIC in the morning with your allopurinol or Uloric. Do not double your dose of ZURAMPIC.

Some patients taking ZURAMPIC may have kidney problems such as a sudden decrease in kidney function (acute kidney failure). This is more common when you take ZURAMPIC without a xanthine oxidase inhibitor. You should always take ZURAMPIC with a xanthine oxidase inhibitor.

Your healthcare professional may do blood tests to check how well your kidneys are working before and during your treatment with ZURAMPIC.

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Important Risk Information

  • Some patients taking ZURAMPIC may have kidney problems such as a sudden decrease in kidney function (acute kidney failure). This is more common when ZURAMPIC is taken without a xanthine oxidase inhibitor such as allopurinol or Uloric
  • ZURAMPIC should always be taken with a xanthine oxidase inhibitor

Do not take ZURAMPIC if you have severe kidney problems, have received a kidney transplant or are on dialysis, have a fast breakdown of cancer cells that can lead to high uric acid (tumor lysis syndrome), or have a rare inherited condition that causes too much uric acid in the blood (Lesch-Nyhan syndrome).

Before taking ZURAMPIC, tell your doctor about all of your medical conditions, including if you:

  • Are pregnant or plan to become pregnant
  • Are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. ZURAMPIC may affect the way other medicines work, and other medicines may affect how ZURAMPIC works.

ZURAMPIC may cause serious side effects including heart problems. People who take ZURAMPIC can have serious heart problems, including heart attack and stroke. It is not known that ZURAMPIC causes these problems.

The most common side effects of ZURAMPIC are headache, flu, higher levels of blood creatinine (a measure of kidney function), and heartburn.

Tell your doctor if you have any side effects that bother you or that do not go away. These are not all of the possible side effects of ZURAMPIC.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

For more information, ask your doctor or pharmacist.

ZURAMPIC is a prescription medicine used together with a xanthine oxidase inhibitor such as allopurinol or Uloric in adults with gout who still have a high uric acid level.

Please see Medication Guide within full Prescribing Information, including BOXED WARNING.

Important Risk Information

  • Some patients taking ZURAMPIC may have kidney problems such as a sudden decrease in kidney function (acute kidney failure). This is more common when ZURAMPIC is taken without a xanthine oxidase inhibitor such as allopurinol or Uloric
  • ZURAMPIC should always be taken with a xanthine oxidase inhibitor

Do not take ZURAMPIC if you have severe kidney problems, have received a kidney transplant or are on dialysis, have a fast breakdown of cancer cells that can lead to high uric acid (tumor lysis syndrome), or have a rare inherited condition that causes too much uric acid in the blood (Lesch-Nyhan syndrome).

Before taking ZURAMPIC, tell your doctor about all of your medical conditions, including if you:

  • Are pregnant or plan to become pregnant
  • Are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. ZURAMPIC may affect the way other medicines work, and other medicines may affect how ZURAMPIC works.

ZURAMPIC may cause serious side effects including heart problems. People who take ZURAMPIC can have serious heart problems, including heart attack and stroke. It is not known that ZURAMPIC causes these problems.

The most common side effects of ZURAMPIC are headache, flu, higher levels of blood creatinine (a measure of kidney function), and heartburn.

Tell your doctor if you have any side effects that bother you or that do not go away. These are not all of the possible side effects of ZURAMPIC.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

For more information, ask your doctor or pharmacist.

ZURAMPIC is a prescription medicine used together with a xanthine oxidase inhibitor such as allopurinol or Uloric in adults with gout who still have a high uric acid level.

Please see Medication Guide within full Prescribing Information, including BOXED WARNING.