ZURAMPIC is a prescription medicine used together with a
xanthine oxidase inhibitor such as allopurinol or Uloric
in adults with gout who still have a high uric acid level.
Some patients taking ZURAMPIC may have kidney problems such
as a sudden decrease in kidney function (acute kidney failure).
This is more common when ZURAMPIC is taken without a xanthine
oxidase inhibitor such as allopurinol or Uloric
ZURAMPIC should always be taken with a
xanthine oxidase inhibitor
Do not take ZURAMPIC if you have severe kidney problems,
have received a kidney transplant or are on dialysis, have a fast breakdown
of cancer cells that can lead to high uric acid (tumor lysis syndrome),
or have a rare inherited condition that causes too much uric acid in the
blood (Lesch-Nyhan syndrome).
Before taking ZURAMPIC, tell your doctor about all of your medical
conditions, including if you:
- Are pregnant or plan to become pregnant
- Are breastfeeding or plan to breastfeed
Tell your doctor about all the medicines you take, including prescription
and over-the-counter medicines, vitamins, and herbal supplements. ZURAMPIC
may affect the way other medicines work, and other medicines may affect
how ZURAMPIC works.
ZURAMPIC may cause serious side effects including heart problems.
People who take ZURAMPIC can have serious heart problems, including heart attack
and stroke. It is not known that ZURAMPIC causes these problems.
The most common side effects of ZURAMPIC are headache, flu,
higher levels of blood creatinine (a measure of kidney function), and heartburn.
Tell your doctor if you have any side effects that bother you or that do
not go away. These are not all of the possible side effects of ZURAMPIC.
For more information, ask your doctor or pharmacist.
including BOXED WARNING.